مقایسه میزان روی سرم در بیماران دیابتی نوع 2 و افراد غیردیابتی

  Z. Salem [1] , R. Vazirinejad [2] , M. Tashakory [3] , P. Balai [4]     Received: 23/02/2010 Sent for Revision: 08/05/2010 Received Revised Manuscript: 31/07/2010 Accepted: 18/08/2010     Background and Objectives : Disturbances of zinc (Zn) homeostasis have been associated with several diseases including diabetes mellitus. The aim of the present study was to compare the serum level of zinc in diabetic type 2 patients with those of non-diabetic control subjects .   Materials and Methods : In this cross-sectional study, 35 diabetic patients referred to the Rafsanjan Diabetes Clinic and 35 healthy non-diabetic controls were selected using simple random sampling method . Both groups aged ≥ 30 and had a similar gender distribution. A pre-designed questionnaire was completed for each participant. A fasting blood sample was individually drawn for fasting blood sugar (FBS) and Zn measurement. The data was then analysed using student's t test.   Results: Results of this study demonstrated that the difference in mean serum level of zinc between the two groups was statistically significant, 10.58 ± 2.27 µg/dl for patient group versus 16.62 ± 5.04 µg/dl for control group (p=0.001). There were no marked differences in terms of age and gender distribitions execpt that for the FBS level.   Conclusion: Our findings showed that the serum level of Zn in the diabetic patients is lower than control group. Further studies are warranted to determine whether zinc supplementation can be used as an adjunct in diabetes management.   Key words: Serum Zinc, Type ll diabetes mellitus, Non Diabetic Control     Funding: This research was funded by Research Council of Rafsanjan University of Medical Sciences.   Conflict of interest: None declared.   Ethical approval: The Ethics Committee of Rafsanjan University of Medical Sciences approved the study .    How to cite this article : Salem Z, Vazirinejad R, Tashakory M, Balai P. Comparison of Serum Zinc Between Type 2 Diabetic Patients and Non Diabetic People: (Short Report) . J Rafsanjan Univ Med Sci 2011 10(3): 225-30. [Farsi]     [1] - Academic Member, Dept. of Social Medicine, School of Medicine, Occupational Environmental Research Center , Rafsanjan University of Medical Sciences, Rafsanjan, Iran   Corresponding Author, Tel: (0391) 5234003, Fax: (0391) 5225209, E-mail: [email protected]   [2] - Associate Prof., Dept. of Epidemiology, School of Medicine, Occupational Environmental Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran   [3] - PhD. Biotechnology, University of Medical Sciences, Rafsanjan, Iran   [4] - General Physician, Ali Ebn Abitaleb Hospital, University of Medical Sciences, Rafsanjan, Iran